What Are the Symptoms and Etiologies of Elevated Cortisol Levels?
What Are the Symptoms and Etiologies of Elevated Cortisol Levels?

I’mCortisol levels can rise in response to stress and certain medical problems. Symptoms of high cortisol include weariness, acne, and weight gain. Hypercortisolism or Cushing syndrom ar noe terms that doctors may use to describe elevated cortisol.
Everyone has high cortisol from time to time, and levels vary throughout the day.
It’s part of your body’s natural response to threats of harm or danger.
However, if your body continually creates too much cortisol, it usually suggests an underlying health concern.
On the other hand, excessive cortisol production on a regular basis typically signals an underlying medical issue.
Continue reading to discover the signs of elevated cortisol, possible causes, and when to seek medical attention.
Symptoms of high cortisol
High cortisol can cause a range of symptoms.
Symptoms can vary depending on what’s causing the increase in your cortisol levels or how highTrusted Source the cortisol levels are.
The following are typical indicators of excessive cortisol:
- weight increase,
- mostly in the face and abdomen Skin thinning, acne,
- and easy bruising Face flushing,
- delayed healing,
- weakened muscles,
- extreme exhaustion,
- agitation, headache,
- and high blood pressure
Reasons for elevated cortisol levels
The anterior pituitary gland releases the adrenocorticotropic hormone (ACTH) in response to the hypothalamus’ release of the corticotrophin-releasing hormone (CRH) when cortisol levels are low. The adrenal gland then produces and releases more cortisol as a result of ACTH.
The adrenal gland may overproduce cortisol for a variety of causes.
Anxiety
Stressors The body uses a mix of hormone and nerve signals, according to a reliable source.
Your adrenal glands release cortisol and adrenaline as a result of these messages.
As a result, the fight-or-flight reaction causes an increase in energy and heart rate.
It’s how your body gets ready for potentially hazardous or damaging circumstances.
In a fight-or-flight scenario, cortisol also aids in limiting any functions that are not absolutely necessary.
Your body functions normally and your hormones revert to normal after the threat has passed.
However, this reaction does not always stop when you are under a lot of stress.
Disorders of the pituitary gland
At the base of your brain is the pituitary gland.
Because it releases hormones to monitor and help regulate various bodily activities, people sometimes call this Trusted Source the “master gland.”
The pituitary gland may overproduce or underproduce hormones, such as ACTH, due to problems, such as malignant pituitary tumors.
tumors of the adrenal glands
Your adrenal glands sit above each kidney.
Adrenal gland tumors can be benign (noncancerous) or malignant (cancerous) and range in size.
Both types can secrete high levels of hormones, including cortisol.
Additionally, you may have pain or a fullness in your belly if the tumor is large enough to press against surrounding organs.
About 1 in 10 patients who have an adrenal gland imaging test will have an adrenal tumor, which is often benign.
Much less common are adrenal malignancies.
Side effects of medication
Finding the right dosage and taking corticosteroids as directed may help lower the risk of developing high cortisol levels.
Certain medications can raise cortisol levels.
For example, corticosteroid medications can cause high cortisol levels if taken in large doses or for an extended period of time.
Steroid medication should never be stopped abruptly without first consulting a physician or gradually decreasing off.
Adrenal insufficiency, in which the adrenal gland stops functioning, can result from abruptly discontinuing.
When is the right time to call a doctor?
You should get a blood test from a doctor if you suspect that your cortisol levels are elevated.
Nonspecific symptoms caused by high cortisol levels could be caused by a number of medical disorders.
The following tests might be suggested by a physician if you are exhibiting symptoms:
- Blood and urine testing for cortisol:
Your blood and urine cortisol levels are measured by these tests. A sample of your blood is taken from your vein for the blood test.
Urine is collected for the cortisol urine test, which is a 24-hour urinary-free cortisol excretion test.
The cortisol levels in the blood and urine samples can then be determined by lab technicians.
- Test for cortisol in saliva:
Saliva taken at night can reveal whether or not your cortisol levels are elevated. During the day, cortisol levels fluctuate, and at night, they fall considerably in those without Cushing disease.
If your nightly cortisol levels are high, you might have Cushing syndrome.
- Imaging examinations:
Imaging procedures such as MRI may be beneficial for acquiring images of your pituitary gland and adrenal glands to look for tumors or other abnormalities.
Elevated cortisol levels can raise your risk. Reliable Source for medical conditions like
- cardiovascular disease
- Osteoporosis
- diabetes
Your doctor can work with you to identify the underlying cause and provide recommendations for appropriate therapies if they discover that your cortisol levels are elevated.
Commonly asked queries
Why does cortisol increase?
Adrenal gland tumors, pituitary gland problems, and stress can all cause an increase in cortisol levels.
How can I tell if my cortisol levels are elevated?
A number of symptoms, including headaches, irritation, and weight gain, can be brought on by elevated cortisol levels.
The symptoms are typically not unique to elevated cortisol levels.
You will need to consult a doctor for a definitive diagnosis, which often needs a blood, saliva, or urine test.
Does vitamin D diminish cortisol levels?
Supplementing with vitamin D may help lower blood and urine cortisol levels, according to some data. But additional study is required.